ENHANCEMENT PATTERNS ON MR MAMMOGRAPHY FOR ABNORMAL NIPPLE DISCHARGE
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- SANUKI Jun-ichi
- Department of Breast Surgery, Shizuoka Cancer Center
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- FUKUMA Eisuke
- Breast Center, Kameda Medical Center
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- UCHIDA Yoshihiro
- Department of Breast Surgery, Shizuoka Cancer Center
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- OKAMOTO Yasukazu
- Department of Breast Surgery, Shizuoka Cancer Center
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- KIMURA Kiyomi
- Department of Breast Surgery, Shizuoka Cancer Center
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- TANAKA Kumiko
- Department of Breast Surgery, Shizuoka Cancer Center
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- SAKAMOTO Naomi
- Breast Center, Kameda Medical Center
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- TSUNODA Yuko
- Breast Center, Kameda Medical Center
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- HIGA Kuniki
- Breast Center, Kameda Medical Center
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- WADAMORI Kenji
- Breast Center, Kameda Medical Center
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- NAGAWA Hirokazu
- Department of Surgical Oncology, The University of Tokyo
Bibliographic Information
- Other Title
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- 乳頭異常分泌症のMRマンモグラフィによるスクリーニング法
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Abstract
The purpose of this study was to evaluate the usefulness of enhancement patterns on MR mammography (MRM) in differentiating between benign and malignant lesions for abnormal nipple discharge (ND). Thirty-five women with ND underwent dynamic contrast enhanced MRM. Histological examination revealed 9 mastopathy, 11 intraductal papilloma, 7 ductal carcinoma in situ (DCIS) and 8 invasive carcinoma in 35 patients. For each lesion, we evaluated the time-intensity curve and two morphological features: distribution and lesion shape. The most reliable morphological pattern indicating benign lesions (mastopathy) was either no specific pattern or diffuse stippled distribution pattern, with a specificity of 10000 (26/26). The most reliable morphological pattern indicating intraductal papilloma was either subareolar clumped pattern, focal-clumped pattern or linear pattern with sensitivity and specificity of 100% (11/11) and 88% (21/24). The most reliable morphological pattern indicating malignancy was segmental distribution pattern with sensitivity and specificity of 93% (14/15) and 90% (18/20). The time-intensity curve was not valuable for screening to diagnose benign lesions in patients with ND. Only for the malignant cases, the time intensity curve helped to indicate the diagnosis with strong initial increase patterns. Morphological features, distribution and lesion shape, and time intensity curve may contribute in screening patients with ND before ductoscopy and biopsy.
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 67 (2), 271-276, 2006
Japan Surgical Association
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Keywords
Details 詳細情報について
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- CRID
- 1390282679825863936
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- NII Article ID
- 130003604862
- 10017507730
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed