A CASE OF VON RECKLINGHAUSEN'S DISEASE ASSOCIATED WITH GASTRIC CANCER, COLONIC CANCER AND SMALL INTESTINAL LEIOMYOMA

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  • ｖｏｎ　Ｒｅｃｋｌｉｎｇｈａｕｓｅｎ病に胃癌，大腸癌，小腸平滑筋腫を合併した１例

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Abstract

We report a case of von Recklinghausen's disease associated with gastric cancer, colonic cancer and small intestinal leiomyoma. The patient was a 73-year-old man complaining of epigastric discomfort. Upper gastrointestinal endoscopy showed a type I tumor at the angular notch of the stomach which was diagnosed as adenocarcinoma by biopsy. During surgery for the gastric carcinoma, advanced cancer in the transverse colon as well as leiomyoma in the jejunum was found. Distal gastrectomy, transverse colectomy, and wedge resection of the jejunum were thus performed. One and a half years later, early cancer was detected in the descending colon and partial colectomy was done. <BR>It has been reported that von Recklinghausen's disease is frequently associated with non-epithelial tumors including neurogenic tumors, but sometimes cases of the disease with malignancies of the digestive organs have recently been reported. This case is so rare that gastric cancer, colonic cancer and small intestinal leiomyoma were associated with the disease.

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