A Case of Recurrent Anaplastic Thyroid Cancer Treated by Lenvatinib after Successful Long-term Multimodal Therapy
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- ONODA Naoyoshi
- Department of Surgical Oncology, Osaka City University Graduate School of Medicine
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- TOKUMOTO Mao
- Department of Surgical Oncology, Osaka City University Graduate School of Medicine
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- NODA Satoru
- Department of Surgical Oncology, Osaka City University Graduate School of Medicine
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- OHIRA Go
- Department of Surgical Oncology, Osaka City University Graduate School of Medicine
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- KASHIWAGI Shinichiro
- Department of Surgical Oncology, Osaka City University Graduate School of Medicine
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- HIRAKAWA Kosei
- Department of Surgical Oncology, Osaka City University Graduate School of Medicine
Bibliographic Information
- Other Title
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- Lenvatinibを投与した治療抵抗性再発甲状腺未分化癌の1例
- 症例 Lenvatinibを投与した治療抵抗性再発甲状腺未分化癌の1例
- ショウレイ Lenvatinib オ トウヨ シタ チリョウ テイコウセイ サイハツ コウジョウセン ミブンカガン ノ 1レイ
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Description
Anaplastic thyroid cancer (ATC) is an extremely aggressive malignancy with dismal prognosis due to resistance to multimodal therapy. Here, we present a case of ATC treated by lenvatinib, a multikinase inhibitor. A 66-year-old Japanese woman was referred to our hospital for the treatment of recurrent ATC on her neck after chemotherapy, surgery, and radio-therapy. The tumor successfully shrank within a month after initiating treatment with lenvatinib. Treatment was interrupted twice for grade 3 hypertension and proteinuria. A rupture of the carotid artery was successfully treated by emergent surgery (ligation of the carotid artery) followed by stent insertion into the subclavian artery.
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 77 (2), 291-295, 2016
Japan Surgical Association
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Details 詳細情報について
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- CRID
- 1390282679827159040
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- NII Article ID
- 130005262475
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- NDL BIB ID
- 030765886
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed