A young patient with neuroendocrine cell carcinoma of the jejunum with multiple liver metastasis

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  • 多発肝転移を伴う20歳男性の空腸原発神経内分泌細胞癌の1例
  • 症例 多発肝転移を伴う20歳男性の空腸原発神経内分泌細胞癌の1例
  • ショウレイ タハツ カン テンイ オ トモナウ 20サイ ダンセイ ノ クウチョウ ゲンパツ シンケイ ナイブンピ サイボウガン ノ 1レイ

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Abstract

A 20-year-old man presented at another hospital with abdominal pain, weight loss, and edema in the lower extremities. He was admitted to our hospital for treatment of anemia and hepatic tumors. Computed tomography revealed perforated jejunal tumor with multiple lymph-node and liver metastasis. We performed partial resection of the jejunum. Histological examination revealed a sheet arrangement of atypical cells. Immunohistochemical staining (chromogranin A, CD56) yielded positive results, and the tumor was diagnosed as neuroendocrine cell carcinoma of the jejunum. After the operation, the patient received 4 courses of chemotherapy with CBDCA and VP-16. However the chemotherapy had little effect, and he died 5 months after the operation. There have been 24 reported cases of neuroendocrine carcinoma of the small intestine in Japan, and our patient was the youngest among all the patients.

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