Long-term Survival after Effective Chemoradiation Therapy on an Outpatient Basis for Stage IVa Esophageal Cancer—Report of a Case—

  • TANAKA Masanao
    Department of Surgery, Takashimadaira Chuo General Hospital Department of Surgery, Shinkatsushika Hospital
  • FUKUSHIMA Ryouji
    Department of Surgery, Teikyo University School of Medicine

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Other Title
  • 外来化学放射線療法が著効し8年生存中であるStage IVa食道癌の1例
  • 症例 外来化学放射線療法が著効し8年生存中であるStage Ⅳa食道癌の1例
  • ショウレイ ガイライ カガク ホウシャセン リョウホウ ガ チョコウシ 8ネン セイゾン チュウ デ アル Stage Ⅳ a ショクドウ ガン ノ 1レイ
  • Long-term Survival after Effective Chemoradiation Therapy on an Outpatient Basis for Stage IVa Esophageal Cancer—Report of a Case—

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Abstract

A 72-year-old woman presented with far advanced esophageal cancer with a total of four lymph nodes metastases at the abdomen and the left supraclavicular fossa. The main lesion was resectable. We decided to perform an esophagectomy without superior mediastinal and cervical lymphadenectomy to avoid excessive invasive operation and to employ postoperative chemoradiation therapy (CRT) to the region left undissected superior mediastinal metastases. In June 2006, we performed subtotal esophagectomy by right thoracotomy and laparotomy and 2-field lymph node dissection. The histopathological diagnosis was type 4 cancer of the lower thoracic esophagus, pT3, pN2 (No3, No9), pStage IVa. After the operation, she removed a jejunostomy tube by herself, for that reoperation was required and CRT could not be started, with resultant enlargement of the 104L metastasis. The patient strongly desired to receive CRT which could be done on an outpatient basis, so that we selected such a palliative therapy as gave Linac X irradiation to the 104L metastasis at a dose of 50 Gy and oral medication of TS-1 alone for 5 years. As a result, the 104L metastasis almost disappeared, and a complete response (CR) has been kept for 8 years without recurrence and metastasis.

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