Treatment of Anal Condyloma Acuminatum Using an Antiviral Ointment.

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  • 抗ウイルス外用剤によるこう門尖圭コンジローマの治療

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Perianal condyloma is a wart caused by human papillomavirus. Since there has been no virus-specific therapy available for this wart, it is not easy to completely eradicate the lesion in a non-invasive way. We thought that vidarabine ointment, an antiviral ointment which has been used to treat herpes simplex virus and herpes zoster virus, could also be effective to eradicate this type of condyloma. Thirteen patients with biopsy-proven anal condyloma acuminatum were prescribed vidarabine ointment. They had to apply it by themselves on their perianal lesion daily for at least 2 weeks. A complete response was achieved in 6 (46%) of the 13 patients and a partial response was achieved in 2 (15%) patients. No response was observed in 5 (39 %) patients. Nine to 32 days were required to detect the change in the complete response cases. There were no side effects nor recurrence. Vidarabine can be effective to eradicate an anal condyloma, and useful as a first-choice treatment.

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