A Case of Anal Malignant Lymphoma Coexistent with Adult T-cell Leukemia

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  • 成人T細胞性白血病が併存した肛門悪性リンパ腫の1例

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Anorectal malignant lymphoma is rare, with an incidence reported to be 0.2% of colorectal malignancy, and anal malignant lymphoma is also quite rare. Anal malignant lymphoma is often associated with homosexual males overseas, related to cellular immunodeficiency, but is rarely seen in Japan. There is no established therapy; although surgery or chemotherapy is effective in some cases, the prognosis is extremely poor. We report a case of anal malignant lymphoma with adult T-cell leukemia, who was found to have HTLV-1 infection. Low-dose CHOP therapy led to early therapy-related death complicated with several infectious diseases. We infer the influence of strong cellular immunodeficiency as a background factor.

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