Analysis of Mortality in Patients with Ulcerative Colitis.

Fukushima T., Koganei K., Shinozaki M., Kito F., Takahashi M., Ohta M., Makino H., Hoshi K.

doi:10.3862/jcoloproctology.54.579

Seven (1.0%) out of 680 patients with ulcerative colitis treated at Yokohama City Hospital died between Aug. 1993 and Feb 2001. They were 5 males and 2 females with a mean age of 44.7 years. Three died from colonic malignant diseases (2 colonic cancers, 1 carcinoid) and 4 died from postoperative complications. The patients that died from malignant disease had not received surveillance colonoscopy, and they died from liver metastasis and/or peritoneal dissemination. Four patients that died from postoperative complications had severe colitis. The postoperative mortality of severe colitis (9.8%, 4/41) was significantly higher than that of operated from the other reasons (0%, 0/190). The amount of prednisolone given within 1 month prior to surgery in the mortality group (1608±710mg) was significantly higher than that in the survived group (451 ±600mg). The cause of death was finally MOF. To reduce mortality, it is important to extend surveillance colonoscopy for the long standing patients and to avoid excess use of steroids preoperatively.

Analysis of Mortality in Patients with Ulcerative Colitis.

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