A Case of an Intracystic Breast Tumor with Difficulties in Preoperative Diagnosis

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  • SENUMA Koji
    Department of Surgery, Juntendo University Shizuoka Hospital
  • SATO Koichi
    Department of Surgery, Juntendo University Shizuoka Hospital
  • WADA Ryo
    Department of Pathology, Juntendo University Shizuoka Hospital

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  • 診断に難渋した20cm大乳腺嚢胞内癌の1例
  • 症例 診断に難渋した20cm大乳腺囊胞内癌の1例
  • ショウレイ シンダン ニ ナンジュウ シタ 20cm ダイ ニュウセンノウホウナイガン ノ 1レイ

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Abstract

A 75-year-old woman noticed a right breast lump in May 2012 which rapidly enlarged for subsequent 13 months. The palpable lump was 20 × 20cm in size when she presented to our hospital. No enlarged axial lymph nodes were palpable. There were medical histories of uterine myoma, colonic cancer and bilateral cataract.<BR>Ultrasonography showed a solid tumor and a core needle biopsy was performed. CT scan and MRI revealed partial thickening with contrast enhancement in the wall of the cystic tumor.<BR>The initial core needle biopsy contained only necrotic and hemorrhagic tissues without viable mammary tissue. The second biopsy revealed a benign papillary epithelial tumor. However, a possibility of malignancy could not be ruled out clinically. The patient thus underwent right mastectomy.<BR>The surgical specimen was histopathologically diagnosed as an intracyctic tumor partially containing papillo-tubular carcinoma (ER+, PgR+, HER2 (1+)). The patient is receiving hormone therapy and has, to date, remained recurrence-free.

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