Electron Microscopic Examination of Platelet-like Body in the Urine of Patients with Renal Diseases and its Comparison with Phase Contrast Microscopic Finding

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  • 腎疾患尿中血小板様小体の電顕的検索と位相差顕微鏡所見との比較
  • ジン シッカン ニョウチュウ ケッショウバンヨウ ショウタイ ノ デンケンテキ

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The authors reported that urine of healthy or sick people always involves platelets or cell elements originated from platelets. These small bodies can be termed as "platelet-like bodies in urine" (U-PLB). The purpose of this study is to examine the U-PLE obtained from the urine of patients with renal diseases. Platelets were found in mechanical renal hematuria caused immediately after percutaneous renal biopsy and in the urine of patient with a suspicuous renal tumor. Transmission electron microscopy (TEM) and scanning electron microscopy (SEM) revealed that the urine ob-tained from a patient with so-called idiopathic renal bleeding, a patient with chronic glomerulone-phritis (CGN) and a patient on the following day of renal allo-transplantation all contained platelets. Platelet-like cells were shown by TENT and SEM in the urine obtained from two patients with acute glomerulonephritis, a patient with CGN and a patient with chronic renal failure. The urine of patients with various renal diseases always contained platelets or platelet-like cells, and cell elements originated from platelets. The urine, in which many disc-shaped U-PLB were found by phase contrast microscopy, contained many platelets or U-PLB, which were shown by TEM.

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