Radioisotope Renoscintigram 曲線におけるSegmentsの再検討

書誌事項

タイトル別名
  • Appraisal of the Analysis of Radioisotope Renogram
  • Radioisotope Renogram キョクセン ニ オケル Segments ノ サイケントウ

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説明

For the appraisal of the quantitative analysis of renogram, the correlation cofficients between renal plasma flow (RPF) and renogram factors were studied. The results of this study revealed that this coefficient was very low. We must have doubt about the definition of renogram segment by Winter. Following investigation was undertaken to elucidate the factors which consist of each segments in renogram. Summary and Conclusions of the experimental studies: 1. When the renal artery was constricted, the upper portion of Segment A changed in accordance with the clearance rate. 2. Renal extraction of radio-hippuran was estimated. It reached to 80% in the first thirty seconds, and at that time the urine specimen contained about 1500 counts/ml of radio-hippuran. 3. By direct injection of radio-hippuran into the renal artery, the true renal elimination curve was obtained, i. e. after the injection the summit of the curve was recorded within 15 seconds, then the plateau curve continued for about one minute, and then followed the slow down-hill curve. Segment B was not observed. 4. Para-amino hippuric acid in high concentration was infused in renal artery before the injection of radio-hippuran. The middle portion of the initial elevation was depressed. 5. When renal-pelvic region was covered with lead plate, Segment A was unchanged, while Segment B and C depressed markedly. 6. Segment A is thought to be consisted not only of the vascularity of the kidney but also of the secretory function of the tubules. 7. In Segment B, there also exists the emission of radio-hippuran in the pelvic region. 8. Minute change in renal hemodynamics can not be indicated by renogram.

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