腎移植後早期尿路感染症とその予防について

  • 葛原 敬八郎
    東京大学医科学研究所臓器移植生理学研究部
  • 杉本 久之
    東京大学医科学研究所臓器移植生理学研究部
  • 高橋 郁夫
    東京大学医科学研究所臓器移植生理学研究部
  • 草場 亮輔
    東京大学医科学研究所臓器移植生理学研究部
  • 山田 豊
    東京大学医科学研究所臓器移植生理学研究部
  • 山内 潤
    東京大学医科学研究所臓器移植生理学研究部
  • 大坪 修
    東京大学医科学研究所臓器移植生理学研究部
  • 秋山 暢夫
    東京大学医科学研究所臓器移植生理学研究部
  • 水野 克己
    東京大学医科学研究所臓器移植生理学研究部
  • 稲生 綱政
    東京大学医科学研究所臓器移植生理学研究部

書誌事項

タイトル別名
  • Early infection of urinary tract after kidney transplantation and its prevention
  • ジン イショクゴ ソウキ ニョウロ カンセンショウ ト ソノ ヨボウ ニ ツイ

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抄録

Infection of urinary tract in early period after renal transplantation is observed relatively often and is responsive usually to medical tretment. Sometimes, it causes depression of the graft function or sepsis. <BR>Therefore, we should make every effort on its prevention. From March. 1975, we proposed to prevent it. We changed urinary drainage method from open system to closed system within 3 days on postoperative course. Furthermore, the irrigation of urethra and bladder before and after catheterization with 0.05% gluconate hibiten solution was added. <BR>In our series the incidence of early infection of urinary tract after renal transplantation had been reduced from 43% (3 out of 7 transplants) in old open system to 0% (9 transplants) in closed system within 3 days postoperatively. <BR>In our series, 33 patients received 34 renal allografts from 33 living related donors and one cadaver donor between July. 1970 and December. 1976. We reviewed 9 cases of the early infection of urinary tract after renal transplantation. <BR>Incidence of the infection were higher in transplants which were drained by urethral catheter over 4 days and those with the urologioal complication. <BR>The infection in the cases with the urological complication had a tendency to become chronic. <BR>The infection occured almost within 2 weeks after transplantation. <BR>The infection had no relation with the urine volume during the drainage. <BR>Pseudomonas was the most frequent pathogen in the infections.

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