糖尿病患者における尿潜血反応陽性の意義

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  • Significance of urine dipstick test for occult blood in patients with diabetes mellitus
  • トウニョウビョウ カンジャ ニ オケル ニョウセンケツ ハンノウ ヨウセイ ノ イギ

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Objective: Hematuria is the usual urinary finding in patients with diabetic nephropathy. In this study, prevalence and significance of microhematuria in patients with diabetes mellitus were investigated.<br>Material and methods: Five hundred and forty-two samples from outpatients, who consulted the Department of Diabetes and Metabolism, were categorized into 4 groups according to the results of the urine dipstick test. Group I: 258 samples, urinary protein (u-P) 1+ and occult blood (OB) negative, group II: 95 samples: u-P 1+, OB1+-3+, group III: 89 samples: u-P 2+-3+, OB negative, group IV 100 samples u-P 2+-3+, OB 1+-3+.<br>Results: Serum concentrations of creatinine and highly sensitive CRP were both significantly higher in group II than in group I. Those parameters were also significantly higher in group IV than in group III.<br>Conclusions: These results indicate that a positive dipstick test for OB may occur in many patients with diabetes mellitus and suggest the progress of renal damage.

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