Rapid Improvement of Osteomalacia by Treatment in a Case with Sjoegren's Syndrome, Rheumatoid Arthritis and Renal Tubular Acidosis Type 1.

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  • OKADA Makoto
    the First Department of Internal Medicine, National Defense Medical College
  • SUZUKI Kimihiro
    the First Department of Internal Medicine, National Defense Medical College
  • HIDAKA Toshihiko
    the First Department of Internal Medicine, National Defense Medical College
  • SHINOHARA Tadashi
    the First Department of Internal Medicine, National Defense Medical College
  • KATAHARADA Koji
    the First Department of Internal Medicine, National Defense Medical College
  • MATSUMOTO Mitsuyo
    the First Department of Internal Medicine, National Defense Medical College
  • TAKADA Kunio
    the First Department of Internal Medicine, National Defense Medical College
  • OHSUZU Fumitaka
    the First Department of Internal Medicine, National Defense Medical College

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  • Rapid Improvement of Osteomalacia by Treatment in a Case with Sjogren's Syndrome, Rheumatoid Arthritis and Renal Tubular Acidosis Type 1

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We present here a case of Sjögren's syndrome (SjS) with osteomalacia based on renal tubular acidosis type 1 (RTA1). A 53-year-old woman, diagnosed as having rheumatoid arthritis (RA) at the age of 33, was admitted to our hospital because of sicca complex, fatigability and worsening general aching. The activity of RA had been low, but it was complicated by SjS, RTA-1 and remarkable osteomalacia. Acidosis was corrected by alkali supplement therapy. By treatment with a regimen consisting of alfacalcidol, calcium L-aspartate, elcatonin and ipriflavone, her bone mineral density (BMD) was remarkably improved within months and the generalized aching gradually diminished.<br>(Internal Medicine 40: 829-832, 2001)

Journal

  • Internal Medicine

    Internal Medicine 40 (8), 829-832, 2001

    The Japanese Society of Internal Medicine

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