Reevaluation of Laboratory Parameters in Relation to Histological Findings in Primary and Secondary Sjogren's Syndrome
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- OHARA Tomoko
- the Department of Clinical Pathology, Jichi Medical School
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- ITOH Yoshihisa
- the Department of Clinical Pathology, Jichi Medical School
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- ITOH Kouichi
- the Department of Clinical Pathology, Jichi Medical School
書誌事項
- タイトル別名
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- Reevaluation of Laboratory Parameters in Relation to Histological Findings in Primary and Secondary Sjoegren's Syndrome.
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Objective We reevaluated the diagnostic value of laboratory parameters in relation to histopathological findings in Sjöögren's syndrome (SS) to clarify whether autoantibodies are useful diagnostic criteria for SS, and whether any laboratory data are useful in estimating the degree of salivary gland change.<br> Patients and Methods Laboratory parameters and histopathological findings were analyzed in 96 patients examined by labial biopsy.<br> Results The percentage of cases with positive assays of rheumatoid factor and anti-SS-A/Ro antibodies was significantly higher in Definite SS. Patients with dense mononuclear cell infiltration of salivary tissues also had higher titers of rheumatoid factor. No useful laboratory parameters were found for the diagnosis of secondary SS.<br> Conclusion Rheumatoid factor and anti-SS-A/Ro antibodies are useful for the diagnosis of primary SS, and rheumatoid factor is also an indicator of the severity of salivary glandular damage.<br>(Internal Medicine 39: 457-463, 2000)
収録刊行物
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- Internal Medicine
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Internal Medicine 39 (6), 457-463, 2000
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679843702272
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- NII論文ID
- 10006994999
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- NII書誌ID
- AA10827774
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- COI
- 1:STN:280:DC%2BD3cvpt1OksQ%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 5384796
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- PubMed
- 10852163
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可