Primary Pulmonary Hypertention Associated with Hypergammaglobulinemia and Autoantibodies

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  • ISOBE Takashi
    The Third Department of Internal Medicine, Kobe University School of Medicine
  • HORIMATSU Tohru
    The Third Department of Internal Medicine, Kobe University School of Medicine
  • SHIRAISHI Nobuyuki
    The Second Department of Pathology, Kobe University School of Medicine
  • MIYAZAKI Kippei
    The Second Department of Pathology, Kobe University School of Medicine
  • IMURA
    The Third Department of Internal Medicine, Kobe University School of Medicine

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  • Primary Pulmonary Hypertention Associat

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Abstract

A case of 38-year-old female with major clinical manifestations of right-sided heart failure associated with Raynaud's phenomenon, positive rheumatoid factor, positive antinuclear factor and hypergammaglobulinemia was reported. Pathological examinations revealed no evidence of angitis. Discrepancy between clinical diagnosis of pulmonary hypertension underlying suspected angitis and pathological diagnosis of primary pulmonary hypertension was discussed.

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