Changes in the Incidence and Etiological Patterns of Bacteremia Associated with Acute Leukemia over a 25-Year Period.
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- FUNADA Hisashi
- The Department of Infectious Prophylaxis, Faculty of Medicine, Toyama Medical and Pharmaceutical University
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- MATSUDA Tamotsu
- The Third Department of Medicine, Faculty of Medicine, Kanazawa University
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説明
During the 25-year period from 1972-1996, 360 episodes of bacteremia occurred in 248 (45%) of a total of 548 patients with acute leukemia on our hematology ward, with the rate of occurrence remaining almost unchanged. Patients with acute nonlymphocytic leukemia, however, had a significant decrease in the incidence of bacteremia during the last 5-year period. Gram-negative bacilli decreased in relative frequency from 64% for the first 15-year period to 40% for the last 5-year period, whereas gram-positive cocci increased from 24% to 51%. Escherichia coli and Enterobacter cloacae somewhat decreased in frequency, whereas coagulase-negative staphylococci and streptococci had considerable increases. In contrast, Pseudomonas aeruginosa was isolated at a relatively constant frequency, forming one of the top two pathogens throughout the study period. Despite the shift toward gram-positive cocci, therefore, P. aeruginosa remains a key organism in considering the initial empiric antibiotic regimen and infection prevention during neutropenia.<br>(Internal Medicine 37: 1014-1018, 1998)
収録刊行物
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- Internal Medicine
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Internal Medicine 37 (12), 1014-1018, 1998
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679844048256
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- NII論文ID
- 10007010443
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- NII書誌ID
- AA10827774
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- COI
- 1:STN:280:DyaK1M7ivFCisw%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 4635326
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- PubMed
- 9932631
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可