Elevated Serum Myosin Light Chain 1 in Influenza Patients

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  • KAJI Masahide
    the Department of Neurology Kurume University, Medical Center
  • KUNO Haruko
    the Department of Neurology Kurume University, Medical Center
  • TURU Toshiomi
    the Department of Neurology Kurume University, Medical Center
  • SATO Yoshihiro
    the Department of Neurology Kurume University, Medical Center
  • OIZUMI Kotaro
    the First Department of Internal Medicine Kurume University

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  • Elevated Serum Myosin Light Chain I in Influenza Patients.

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Objective Myocarditis has been described as a complication of influenza. Patients with influenza may have symptoms and abnormal laboratory data (including chest X-ray, electrocardiogram, etc.) suggestive of myocarditis, although few observations have been made regarding the prevalence of asymptomatic myocardial injury. We investigated whether influenza can produce myocardial injury without cardiac symptoms.<br> Methods During the epidemic of influenza A (H3N2) from 1998 to 1999 in Japan, we examined possible cardiac muscle damage associated with influenza in patients without apparent clinical myocardial injury by measuring serum myosin light chain concentrations.<br> Patients Ninety-six influenza-positive patients (46 males and 50 females, average age 43.4 years) without impaired renal function were studied.<br> Results Of these patients, 11 (11.4%) had elevated serum myosin light chain I concentrations.<br> Conclusion Asymptomatic myocardial injury may be present in patients with influenza even when they have no symptoms suggestive of myocardial injury.<br>(Internal Medicine 40: 594-597, 2001)

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  • Internal Medicine

    Internal Medicine 40 (7), 594-597, 2001

    一般社団法人 日本内科学会

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