Giant Hydronephrosis due to a Ureteral Stone, and Elevated Serum Levels of CA 19-9.

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  • Elevation of Serum CA19-9 Levels in Benign Diseases

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CA 19-9 is a widely used tumor marker. However, an elevation in serum CA 19-9 can occur in some patients with benign disorders such as cholecystolithiasis in the absence of tumor. We treated a case of acquired ureteral stone-induced giant hydronephrosis with markedly elevated serum CA 19-9 values. After nephrectomy, the serum CA 19-9 level returned to normal. No malignant cells were found in the tissues of the resected kidney. Localization of CA 19-9 was confirmed by immunohistochemical staining of the renal pelvic mucosa. A detailed case report is presented with a review of the literature.<br>(Internal Medicine 38: 887-891, 1999)

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  • Internal Medicine

    Internal Medicine 38 (11), 887-891, 1999

    The Japanese Society of Internal Medicine

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