Meningitis Carcinomatosa Originating from an Alpha Fetoprotein-producing Gastric Cancer.

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  • TSUJIKAWA Tomoyuki
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • TSUKAMOTO Hirotaka
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • ITOH Akihiko
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • ANDOH Akira
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • SASAKI Masaya
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • KOYAMA Shigeki
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • FUJIYAMA Yoshihide
    the Second Department of Internal Medicine, Shiga University of Medical Science
  • BAMBA Tadao
    the Second Department of Internal Medicine, Shiga University of Medical Science

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Description

Alpha fetoprotein (AFP)-producing gastric cancer is relatively rare and meningitis carcinomatosa is similarly a rare manifestation among the neoplastic diseases. There have been no previous reports of meningitis carcinomatosa originating from AFP-producing gastric cancer. A 68-year-old man with AFP-producing gastric cancer was treated with cisplatin and doxifluridine because of multiple liver metastases. Although the liver lesion was reduced to 30% of pretreatment size after 6 courses of chemotherapy, meningitis carcinomatosa subsequently occurred. Immunostaining of AFP and magnetic resonance imaging (MRI) were useful in the diagnosis of meningitis caused by AFP producing cancer cells.<br>(Internal Medicine 39: 223-227, 2000)

Journal

  • Internal Medicine

    Internal Medicine 39 (3), 223-227, 2000

    The Japanese Society of Internal Medicine

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