Acute Renal Failure after Binge Drinking of Alcohol and Nonsteroidal Antiinflammatory Drug Ingestion.

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  • TSUBOI Nobuo
    The Department of Internal Medicine, Saiseikai Central Hospital The Second Department of Internal Medicine, Jikei University School of Medicine
  • YOSHIDA Hiroaki
    The Department of Internal Medicine, Saiseikai Central Hospital The Second Department of Internal Medicine, Jikei University School of Medicine
  • SHIBAMURA Kazuhisa
    The Department of Internal Medicine, Saiseikai Central Hospital
  • HIKITA Miho
    The Department of Internal Medicine, Saiseikai Central Hospital The Second Department of Internal Medicine, Jikei University School of Medicine
  • TOMONARI Haruo
    The Department of Internal Medicine, Saiseikai Central Hospital The Second Department of Internal Medicine, Jikei University School of Medicine
  • KURIYAMA Satoru
    The Department of Internal Medicine, Saiseikai Central Hospital The Second Department of Internal Medicine, Jikei University School of Medicine
  • SAKAI Osamu
    The Second Department of Internal Medicine, Jikei University School of Medicine

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  • Acute Renal Failure after Binge Drinkin

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A case of reversible acute renal failure (ARF) following binge drinking together with the transient use of a nonsteroidal antiinflammatory drug (NSAID) is described. After binge drinking, the patient experienced hyperdipsia, and the volume of his urine decreased. Subsequently, he took an NSAID to relieve systemic joint pain associated with low grade fever, and then he had complete anuria. One day after taking the NSAID, he visited our hospital, and was found to have severe renal dysfunction accompanied by severe liver damage (blood urea nitrogen and creatinine concentrations were 57 and 5.4 mg/dl, respectively). The impaired renal function progressed over the first three hospital days, as reflected by an elevated creatinine concentration to 11.6 mg/dl. Nine treatment sessions of hemodialysis were, therefore, required to recover the loss of renal function. The present case suggests that binge drinking may be a potential risk factor for ARF in the presence of NSAIDs.<br>(Internal Medicine 36:102-106, 1997)

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  • Internal Medicine

    Internal Medicine 36 (2), 102-106, 1997

    一般社団法人 日本内科学会

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