An Autopsy Case of Wegener''s Granulomatosis with Pachymeningitis
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- TOJO Jun
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- NISHIMAKI Tomoe
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- OHYANAGI Hironobu
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- SAITO Ayako
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- OHIRA Hiromasa
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- SAKA Mitsuru
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- KURODA Masahito
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- ISHIKAWA Hidemasa
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
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- KASUKAWA Reiji
- The Department of Internal Medicine II, Fukushima Medical University, School of Medicine
Bibliographic Information
- Other Title
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- An Autopsy Case of Wegener′s Granulomatosis with Pachymeningitis
- Autopsy Case of Wegener s Granulomatosi
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Abstract
A 61-year-old woman presented with high fever, headache and left facial palsy with diplopia. Histopathological examination of the biosied specimens taken from nasal mucosa and kidney revealed a granulomatous angiitis with giant cell infiltration. Ga-DTPA-enhanced magnetic resonance imaging (MRI) revealed a thickening of dura mater in the middle cranial fossa and tentorium cerebelli. The observed left facial and occulomotor palsy was considered to be caused by pachv meningitis associated with Wegener's granulomatosis (WG). Cyclophosphamide combined with prednisolone effectively improved the symptoms. However, the patient died of acute interstitial pneumonitis, presumably caused by cyclophosphamide. The pathohistology obtained in the autopsy revealed a fibrous thickening of the dura mater in the left meningen with a segmental scarring of the arteries and a necrotizing arteritis in the kidney.<br>(Internal Medicine 37: 711-715, 1998)
Journal
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- Internal Medicine
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Internal Medicine 37 (8), 711-714, 1998
The Japanese Society of Internal Medicine
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Details 詳細情報について
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- CRID
- 1390282679845417216
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- NII Article ID
- 10009507732
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- NII Book ID
- AA10827774
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- COI
- 1:STN:280:DyaK1cvhs12ntg%3D%3D
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- ISSN
- 13497235
- 09182918
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- NDL BIB ID
- 4555848
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- PubMed
- 9745862
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed