Syndrome of Inappropriate Secretion of Antidiuretic Hormone and Thrombocytopenia Caused by Cytomegalovirus Infection In a Young Immunocompetent Woman

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  • SATO Hiroe
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • KAMOI Kyuzi
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • SAEKI Takako
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • YAMAZAKI Hajime
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • KOIKE Tadashi
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • MIYAMURA Syoji
    Department of Internal Medicine, Nagaoka Red Cross Hospital
  • GEJYO Fumitake
    Department of Internal Medicine, Niigata University School of Medicine

書誌事項

公開日
2004
資源種別
journal article
DOI
  • 10.2169/internalmedicine.43.1177
公開者
一般社団法人 日本内科学会

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説明

We report the first case of the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with cytomegalovirus (CMV) infection. A 32-year-old woman was admitted to our hospital because of pandysautonomic signs and symptoms. Thrombocytopenia and hyponatremia were present. Serum anti-CMV IgM and IgG antibodies were positive. Despite hyponatremia, urinary osmolality exceeded plasma osmolality and plasma vasopressin levels related to plasma osmolality were high. Restriction of water intake and administration of dimethylchlorotetracycline improved hyponatremia, suggesting this patient had SIADH. In this patient, SIADH may have been caused by acute pandysautonomia that developed following CMV infection.

収録刊行物

  • Internal Medicine

    Internal Medicine 43 (12), 1177-1182, 2004

    一般社団法人 日本内科学会

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