Serum Hemoglobin Level Determined at the First Presentation is a Poor Prognostic Indicator in Patients with Lung Cancer
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- AOE Keisuke
- Second Department of Medicine, Okayama University Medical School Department of Respiratory Medicine and Clinical Research, NHO Sanyo National Hospital, Respiratory Disease Center, Yamaguchi
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- HIRAKI Akio
- Second Department of Medicine, Okayama University Medical School
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- MAEDA Tadashi
- Second Department of Medicine, Okayama University Medical School Department of Respiratory Medicine and Clinical Research, NHO Sanyo National Hospital, Respiratory Disease Center, Yamaguchi
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- KATAYAMA Hideki
- Second Department of Medicine, Okayama University Medical School Department of Respiratory Medicine and Clinical Research, NHO Sanyo National Hospital, Respiratory Disease Center, Yamaguchi
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- FUJIWARA Keiichi
- Second Department of Medicine, Okayama University Medical School Department of Respiratory Medicine and Clinical Research, NHO Sanyo National Hospital, Respiratory Disease Center, Yamaguchi
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- TABATA Masahiro
- Second Department of Medicine, Okayama University Medical School
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- KIURA Katsuyuki
- Second Department of Medicine, Okayama University Medical School
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- UEOKA Hiroshi
- Second Department of Medicine, Okayama University Medical School Department of Respiratory Medicine and Clinical Research, NHO Sanyo National Hospital, Respiratory Disease Center, Yamaguchi
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- TANIMOTO Mitsune
- Second Department of Medicine, Okayama University Medical School
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Objectives Anemia is observed in various malignancies including lung cancer and is recently considered to be a poor prognostic indicator. We investigated whether there is a correlation between anemia, other clinicopathologic factors, and survival.<br>Methods We retrospectively examined the clinical records of 611 patients with lung cancer.<br>Results Of those, 298 (48.8%) patients had anemia at the time of their first visit to our hospital. There was a significant correlation between anemia and age (p=0.0006) or ECOG performance status (p=0.0002), however, there was no correlation of anemia with gender, histological type, clinical stage, or serum level of lactate dehydrogenase. Survival was significantly shorter in 298 patients with anemia (median survival time (MST): 7.5 months) compared with 313 patients without anemia (MST: 11.8 months, p<0.0001). Multivariate analysis of prognostic factors using the Cox proportional hazards model revealed that anemia appeared to be an independent prognostic indicator.<br>Conclusion Anemia observed at the first presentation is an independent poor prognostic indicator in patients with lung cancer.
収録刊行物
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- Internal Medicine
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Internal Medicine 44 (8), 800-804, 2005
一般社団法人 日本内科学会
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詳細情報 詳細情報について
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- CRID
- 1390282679846444672
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- NII論文ID
- 130000076339
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- NII書誌ID
- AA10827774
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 7402058
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- PubMed
- 16157976
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可