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Changes in the Urinary Excretion of .BETA.2-Microglobulin (.BETA.2MG) and N-acety-.BETA.-D-glucosaminidase (NAG) during Treatment for Lupus Nephritis
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- Masuda Takahiro
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Akimoto Tetsu
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Ando Yasuhiro
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Kobayashi Takahisa
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Meguro Daishi
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Muto Shigeaki
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Ueda Yoshihiko
- Department of Pathology, Dokkyo Medical University Koshigaya Hospital
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- Yumura Wako
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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- Kusano Eiji
- Division of Nephrology, Department of Internal Medicine, Jichi Medical University
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Description
Tubulointerstitial involvement in the kidneys is frequently found but it is a less emphasized feature of lupus nephritis (LN). Recent studies have shown increases in the urinary excretion of β2-microglobulin (β2MG) and N-acetyl-beta-D-glucosaminidase (NAG), which are considered to indicate the presence of tubulointerstitial damage, particularly in cases of LN. However, the changes in these urinary parameters during the clinical course of LN have not yet been fully clarified. In this report, we describe the changes in the urinary excretion of β2MG and NAG during immunosuppressive treatment combined with double filtration plasmapheresis in a case of LN.<br>
Journal
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- Internal Medicine
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Internal Medicine 47 (4), 287-290, 2008
The Japanese Society of Internal Medicine
