Cerebral Sinus Thrombosis and Heparin-induced Thrombocytopenia in a Patient with Paroxysmal Nocturnal Hemoglobinuria
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- Ishihara-Kawase Kayoko
- Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences
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- Ohtsuki Toshiho
- Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences
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- Sugihara Sayaka
- Department of Hematology and Oncology, Division of Clinical and Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University Graduate School of Biomedical Sciences
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- Tanaka Hitomi
- Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences
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- Nakamura Takeshi
- Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences
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- Kimura Akiro
- Department of Hematology and Oncology, Division of Clinical and Experimental Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University Graduate School of Biomedical Sciences
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- Matsumoto Masayasu
- Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical Sciences
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説明
Paroxysmal nocturnal hemoglobinuria is a rare acquired disorder of clonal hematopoietic stem cells and it is characterized as a hypercoagulable disorder. We report a 36-year-old woman with the rare triad of paroxysmal nocturnal hemoglobinuria, cerebral sinus thrombosis triggered by infection, and rapid-onset heparin-induced thrombocytopenia after resensitization of heparin. This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 49 (10), 941-943, 2010
一般社団法人 日本内科学会