IgG4-related Chronic Tubulointerstitial Nephritis without Autoimmune Pancreatitis and the Time Course of Renal Function
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- Tsubata Yutaka
- Department of Internal Medicine, Niigata Prefectural Central Hospital
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- Oya Takeshi
- Department of Pathology, Niigata Prefectural Central Hospital
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- Nishi Shinichi
- Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
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- Narita Ichiei
- Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
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- Akiyama Fumihiro
- Department of Internal Medicine, Niigata Prefectural Central Hospital
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- Ajiro Junya
- Department of Internal Medicine, Niigata Prefectural Central Hospital
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- Saeki Takako
- Department of Internal Medicine, Nagaoka Red Cross Hospital
書誌事項
- 公開日
- 2010
- DOI
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- 10.2169/internalmedicine.49.3787
- 公開者
- 一般社団法人 日本内科学会
この論文をさがす
説明
We report an elderly man with chronic tubulointerstitial nephritis (TIN) showing a high serum immunoglobulin G4 (IgG4) concentration. His serum creatinine (Scr) level had gradually increased from 0.9 mg/dL to 5.6 mg/dL over 18 months. Renal biopsy showed marked IgG4-positive plasma cell infiltration in the interstitium without glomerular abnormalities and IgG4-related TIN was diagnosed. Oral prednisolone reduced his Scr and IgG4 levels immediately. The present case indicates that IgG4-related TIN can not only progress rapidly but also chronically over a long period without significant urinary abnormalities, and we should consider hidden IgG4-related TIN in cases of chronic renal insufficiency.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 49 (15), 1593-1598, 2010
一般社団法人 日本内科学会
