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Poorly Differentiated Gastric Adenocarcinoma Can Mimic Hilar Cholangiocarcinoma
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- Urasaki Tetsuya
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Kodaira Makoto
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Hibino Masaki
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Yamagata Shingo
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Watanabe Yukihiro
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Terazawa Yasuyuki
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Sano Munetaka
- Department of Gastroenterology, Yaizu City Hospital, Japan
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- Kuriki Ken
- Department of Diagnostic Pathology, Yaizu City Hospital, Japan
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Description
This report describes two cases with obstructive jaundice caused by poorly differentiated gastric adenocarcinoma. Computed tomography scans showed circumferential stenosis in the hilar bile ducts. Endoscopic retrograde cholangiopancreatography showed dilatation of the bilateral hepatic ducts and stenosis of the common hepatic ducts from the bifurcation of the bilateral hepatic ducts. The first diagnoses were hilar cholangiocarcinoma and biliary drainage decreased serum bilirubin; however, both patients died of cancer within a short period of time. Autopsies revealed lymphatic vessel invasion and possible subepithelial invasion by gastric adenocarcinoma into the hilar bile ducts. A differential diagnosis should thus be required in suspected cases of hilar cholangiocarcinoma.
Journal
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- Internal Medicine
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Internal Medicine 55 (12), 1559-1564, 2016
The Japanese Society of Internal Medicine