Long-term survival of two patients with esophageal neuroendocrine carcinoma who underwent multidisciplinary therapy

  • Gotoda Tatsuhiro
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Kawano Seiji
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Kono Yoshiyasu
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Miura Kou
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Kanzaki Hiromitsu
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Iwamuro Masaya
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Kawahara Yoshiro
    Department of Endoscopy, Okayama University Hospital
  • Tanaka Takehiro
    Department of Pathology, , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Yoshino Tadashi
    Department of Pathology, , Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Shirakawad Yasuhiro
    Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Tabata Masahiro
    Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Tanimoto Mitsune
    Department of Hematology and Oncology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Okada Hiroyuki
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Endoscopy, Okayama University Hospital

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Other Title
  • 集学的治療により長期生存が得られた食道神経内分泌癌の2例
  • 症例報告 集学的治療により長期生存が得られた食道神経内分泌癌の2例
  • ショウレイ ホウコク シュウガクテキ チリョウ ニ ヨリ チョウキ セイゾン ガ エラレタ ショクドウ シンケイ ナイブンピガン ノ 2レイ

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Abstract

Esophageal neuroendocrine carcinoma (ECC) is rare and has a poor prognosis when presenting with vascular invasion and distant metastasis from an early stage. Multidisciplinary therapy with surgery, chemotherapy, and radiation therapy may prolong survival in patients with advanced ECC, but there is as yet no standard therapy for advanced ECC. We treated two patients who have achieved long-term survival (> 4 years) who underwent multidisciplinary therapy, including chemotherapy, for ECC. Our experience with these two cases suggests that multidisciplinary therapy, including chemotherapy, may be effective for treating ECC at an advanced stage.

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