Falciparum Malaria Incidentally Pretreated with Azithromycin

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  • Shibahara Daisuke
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Kinjo Takeshi
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Nishiyama Naoya
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Kami Wakaki
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Nabeya Daijiro
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Haranaga Shusaku
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Higa Futoshi
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Tateyama Masao
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan
  • Shinzato Takashi
    Division of Infectious Diseases and General Internal Medicine, Nakagami General Hospital, Japan
  • Toma Hiromu
    Department of Parasitology and Immunopathoetiology, Graduate School of Medicine, University of the Ryukyus, Japan
  • Kishimoto Hidehiro
    Department of Parasitology and Immunopathoetiology, Graduate School of Medicine, University of the Ryukyus, Japan
  • Fujita Jiro
    Department of Infectious Diseases, Respiratory and Digestive Medicine, Faculty of Medicine, University of the Ryukyus, Japan

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Description

A 65-year-old man, who recently returned from Liberia, visited a clinic complaining of fever, and azithromycin was prescribed. The patient presented to a general hospital 5 days after the onset of symptoms, however, a blood smear examination failed to detect malaria. Contrary to the blood smear result, a rapid antigen test in our hospital was strongly-positive for falciparum malaria, indicating a high level of malarial antigen in the blood. Moreover, laboratory examinations on admission showed a tendency for improvement. We assumed that the administration of azithromycin partially treated malaria, thus complicating the blood smear diagnosis. We should be careful in prescribing azithromycin, which is widely used in clinics, to travelers returning from malaria-endemic countries.<br>

Journal

  • Internal Medicine

    Internal Medicine 54 (19), 2513-2516, 2015

    The Japanese Society of Internal Medicine

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