The mutual effects of Cd<sup>2+</sup> and ruthenium red on rat liver mitochondrial energy transfer reaction

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  • HASEGAWA Tohoru
    Department of Public Health, Okayama University Medical School
  • NOGAMI Yusaku
    Department of Public Health, Okayama University Medical School
  • OGATA Masana
    Department of Public Health, Okayama University Medical School

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Other Title
  • 環境汚染物質(重金属など)の生体膜に対する作用 第3報 カドミウムとルテニウムレッドの相互作用,特にミトコンドリアの酸化的リン酸化反応に対して
  • 環境汚染物質(重金属など)の生体膜に対する作用-3-カドミウムとルテニウムレッドの相互作用,特にミトコンドリアの酸化的リン酸化反応に対して
  • カンキョウ オセン ブッシツ ジュウキンゾク ナド ノ セイタイ マク ニ タ

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Abstract

The mutual effects of Cd2+ and ruthenium red on rat liver mitochondrial energy transfer reaction are described. In results, ruthenium red recovered the depression of the oxidative phosphorylation induced by Cd2+. Ruthenium red suppressed the K+ release induced by Cd2+. As the binding site of the Cd2+ have other than the binding site of ruthenium red, the site of ruthenium red is greatly related with the inhibitory effect of Cd2+ and this site is similar to the binding site of Ca2+.

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