位相差顕微鏡(PCM)観察による穿刺液の細胞学的研究

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書誌事項

タイトル別名
  • Cytological Studies on the Aspirated Fluid With the Phase Contrast Microscope
  • 第4編 腫瘍性腹水の細胞学的研究附.全編のまとめ
  • Part 4. A ctyological Study on Tumorous Ascites
公開日
1960
DOI
  • 10.4044/joma1947.72.3_875
公開者
岡山医学会

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説明

As a continuation to Part 3 the author carried out observations on the tumor cells in tumorous ascites with the aid of a phase contrast microscope, and also on other cells such as phagocytes, and obsained some noteworthy results as follows.<br>1. When tumorous acites is divided into three groups according to the rate of tumor cell appearance: namely, group I those showing less than 5 per cent of tumor cells, group II those showing over 20 per cent, and group III those showing no fixed percentage; gastric cancer ascites, cancerous peritonitis, and cancerous ascites belong to the respective group in the order mentioned.<br>2. The case in which tumor cells and tumorous signet-ring cells can be verified is designated as the direct symptom, while those specific characteristics in tumorous ascites showing cells other than tumor cells, such as phagocytes and seruous cells, are to be designated as the indirect symptoms.<br>3. Tumor cells themselves will assume various shapes according to the kind of tumor and by their morphological characteristics even gastric cancer can be distinguished as glandular, simple, solid, or colloidal cancers. And likewise ccelothelioma cells present still more specific morphological traits, revealing a transformation picture to serous cells. In liver cancer cells there are specific granules, and sarsoma cells of reticulosarcoma and others present characteristics different from cancer cells.<br>4. Viewing the indirect symptom, phagocytes look ugly and serous cells show a strong degenerative tendency or a strong atypical appearance, and neutrophils also degenerate rapidly. From these findings cancer can be readily distinguisshed from other diseases such as liver cirrhosis, tuberculous peritonitis, etc.<br>5. Cytological observations of ascites as carried throughout parts 3 and 4 clearly prove to be a useful method for the clinical differential diagnosis of ascites in various diseases.

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