神経性食欲異常症に伴ったPseudo-Bartter症候群の1例

DOI Web Site
  • 松林 直
    九州大学医学部心療内科:大阪労働衛生センター第一病院心療内科
  • 高市 幸彦
    九州大学医学部心療内科:大阪労働衛生センター第一病院心療内科
  • 田中 実
    大阪労働衛生センター第一病院内科
  • 谷北 明彦
    大阪労働衛生センター第一病院内科
  • 高橋 佳代子
    大阪労働衛生センター第一病院心療内科
  • 長井 啓介
    Department of Psychosomatic Medicine, Faculty of Medicine, Kyushu University:Department of Psychosomatic Medicine, Daiichi Hospital, Osaka Labor Hygiene Center
  • 玉井 一
    九州大学医学部心療内科
  • 中川 哲也
    九州大学医学部心療内科

書誌事項

タイトル別名
  • A Case of Pseudo-Bartter Syndrome Associated with Dysorexia Nervosa
  • シンケイセイ ショクヨク イジョウショウ ニ トモナッタ Pseudo Bar

この論文をさがす

抄録

We encountered a 37-year-old woman with dysorexia nervosa (bulimia, vomiting, amenorrhea and obese-aversion) satisfied the criteria for Pseudo-Bartter syndrome, including hypokalemia, hyper-plasma renin activity, normal blood pressure, and poor response against exogenous angiotensin II/angiotensin II analogue as a result of self-administration of Colac^[○!R] (Bisacodyl) 50mg/day for more than 5 years. It was considered that the cause of hypokalemia was due to the excessive potassium excretino into the feces, 26.0mEq/day (potassium in diet, 70mEq/day). On the other hand, the urine potassium secretion was very low. Hormonal examination and thyroid aspiration biopsy revealed euthyroid chronic thyroiditis histologically, low T_3 syndrome and abnormal hGH response after TRH bolus injectin. The correlation between chronic thyroiditis and Pseudo-Bartter syndrome was unknown. Various drugs were administered to normalize serum potassium concentration. Exogenous potassium, Captopril, Indomethacin, Spironolactone were not effective. But only 2mg/day of Loperamide, antagonist prostaglandin-induced diarrhea, was effective. As long as the authors are aware, this is the first report that Loperamide is useful in hypokalemia of Pseudo-Bartter syndrome.Psychosomatic approach to the patient led to the insight for the mechanism of the disease. Eating attitude test (EAT) score was also improved.

収録刊行物

  • 心身医学

    心身医学 25 (6), 523-528, 1985

    一般社団法人 日本心身医学会

詳細情報 詳細情報について

問題の指摘

ページトップへ