Psychosomatic Studies on Intractable Gastric Ulcers by Famotidine

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  • 難治性胃潰瘍に関する心身医学的検討
  • ナンジセイ イ カイヨウ ニ カンスル シンシン イガクテキ ケントウ

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Abstract

We studied psychosocial factors affecting the healing time of gastric ulcers. We compared following factors between 33 patients with gastric ulcers cured by Famotidine 40 mg per day in 3 months (Group 1) and 20 patients with intractable ulcers over 6 months (Group 2). Cornell Medical Index, Self Rating Questionnaire for Depression and MMPI Alexithymia Scale were carried out, but in each score there was no significant difference between Group 1 and Group 2. Background factors mainly focused on the style of living were compared. The results indicated that 1) patients with intractable gastric ulcers drank more cups of coffee (p<0.05), 2) had more irregular working time (p<0.05), 3) felt more mental stress (p<0.05), 4) experienced more recurrence of gastric ulcers (p<0.05), 5) and eventually ulcers became difficult to treat despite young age (p<0.01), 6) had less past history of other diseases (p<0.01). This study showed that life style and biological factors played more important roles in the prolongation of healing time of gastric ulcer than psychological traits.

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