Stress Polycythemia and Organ Choice(On the Organ Choice in Psychosomatic Disorders)

DOI Web Site 15 References
  • Murakami Masato
    First Department of Internal Medicine, Nihon University School of Medicine:Department of Psychosomatic Medicine, Nihon University Hospital
  • Matsuno Toshio
    Department of Psychosomatic Medicine, Nihon University Hospital
  • Ueda Masao
    Stress Science Institute, Public Health Research Center
  • Ebana Shoichi
    Department of Psychosomatic Medicine, Yokohama Rousai Hospital
  • Kashihara Hidetoshi
    PL Tokyo Health Management Center
  • Tamura Masaki
    PL Tokyo Health Management Center
  • Koike Kazuyosi
    Division of Clinical Research, Nihon University School of Dentistry
  • Katsura Taisaku
    LCC Institute for Stress Medicine
  • Horie Takashi
    First Department of Internal Medicine, Nihon University School of Medicine:Department of Psychosomatic Medicine, Nihon University Hospital

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Other Title
  • ストレス多血症と器官選択(心身症における器官選択について)(第39回日本心身医学会総会)
  • ストレス多血症と器官選択
  • ストレス タケツショウ ト キカン センタク

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Stress (spurious) polycythemia is a pathological condition induced by psychosocial events and emotional stress in which the erythrocyte component in the blood abnormally increases. It induces increased blood viscosity and may cause thrombus formation, which may develop into the cerebrovascular accident or ischemic heart disease in a certain condition. We studied the etiology and involvement of psychosocial stress factors, and physiological factors, and considered the relationship between the stress and organ choice. Stress polycythemia is often seen in very active individuals when they are driven into a stressful situation, but some distorted personality such as neurotic state, cyclothymia, or depressive state may also participate in the formation of polycythemia. Erythrocyte component often increases or decreases with the change of circumstances and sometimes returns to normal when sufficient relaxation is acquired. Elevation of erythrocyte component may play a more important role than relative water loss for the formation of polycythemia because viscosity of whole blood increases as the hemoglobin increases whereas plasm viscosity does not. When people have certain physiological propensities of the autonomic nervous system and endocrine system along with certain personal trait and behavioral characteristics, they may develop polycythemia under psychosocial or physical stress. Our studies showed that the elevated plasma catecholamine often associates with the elevation of red blood cells, white blood cells, platelets and PF4 (platelet factor-4) . It is essential to pay more attension to the distorted behavior of daily life and alteration of life style is important for prevention and treatment of circulatory disorders induced by the stress polycythemia.

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