Difference in Respiratory Responses between Near-fatal Asthma and Non-near-fatal Asthma

DOI Web Site 3 Citations 13 References
  • Mashima Ichiro
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Fujimura Takeo
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Shimizu Natsue
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Ebe Yuusuke
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Saitou Isao
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Murakami Shuuichi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Katagiri Atsuko
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Yoshimine Fumitoshi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Hasegawa Takashi
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Muramatsu Yoshiyuki
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Gejyo Fumitake
    Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences
  • Tanaka Yutaka
    Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Course for Oral Sciences
  • Satou Mai
    School of Health Sciences, Faculty of Medicine, Niigata University
  • Matsudo Saori
    School of Health Sciences, Faculty of Medicine, Niigata University

Bibliographic Information

Other Title
  • Near-fatal asthmaとnon-near-fatal asthmaにおける換気応答の相違
  • Near-fatal asthmaとno-near-fatal asthmaにおける換気応答の相違
  • Near fatal asthma ト no near fatal asthma ニ オケル カンキ オウトウ ノ ソウイ

Search this article

Abstract

Objectives: We carried out a study with an aim to verify if: (1) there is a difference in respiratory responses between near-fatal asthma (NFA) patients and Non-NFA patients; (2) there is a difference in psychological characteristics between NFA patients and Non-NFA patients relating to respiratory responses. Subjects: The study population included 10 patients (5 NFA and 5 Non-NFA) referred from the outpatient clinic of Niigata University Medical and Dental Hospital. Method: We examined whether or not dyspnea and chemosensitivity to hypoxia and hypercapnia and resistive load are different between NFA patients and Non-NFA patients. Patients were administered a self-rated psychological measures, including the Japanese version of the Hospital Anxiety and Depression Scale (HADS). Results: The mean value of visual analog scale (VAS) (perception of dyspnea) during resistive loaded breathing was significantly higher in NFA patients than in Non-NFA patients (p=0.00). There was a relation between maximal values of VAS and both anxiety (r=-0.51) and depression (r=-0.67) during resistive loaded breathing in Non-NFA patients. The mean value of slope of the minute ventilation (V_E) (Change in V_E/Change in VAS) was significantly lower (p=0.03) in NFA patients than in Non-NFA patients during resistive loaded breathing. The mean value of duty ratio in hyperoxic hypercapnic responses was significantly higher in NFA patients than in Non-NFA patients (p=0.00). There was a relation between values of VAS and values of duty ratio in hyperoxic hypercapnic responses in NFA patients (r=0.82). Conclusion: These results have clinical implications for managing asthma. We need to know the characteristics of perception of dyspnea in asthma.

Journal

Citations (3)*help

See more

References(13)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top