Interpretation of Bloating Feeling and Epigastric Pain : with a View of Gastric Function(Symposium/Brain-gut Interaction in the Pathophysiology of Functional Dyspepsia)
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- Konagaya Toshihiro
- Marine Clinic:Department of Gastroenterology, Nagoya University
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- Kaneko Hiroshi
- Department of Neurology (Psychosomatic Medicine), Banbuntane Houtokukai Hospital, Fujita Health University
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- Funaki Yasushi
- Clinical Laboratory Center, Aichi Medical University Hospital
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- Iida Akihito
- Department of Internal Medicine (Division of Gastroenterology), Aichi Medical University
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- Matsunaga Masahiro
- Department of Neurology (Psychosomatic Medicine), Banbuntane Houtokukai Hospital, Fujita Health University
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- Kasugai Kunio
- Department of Internal Medicine (Division of Gastroenterology), Aichi Medical University
Bibliographic Information
- Other Title
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- 消化管機能からみた腹部膨満感,上腹部痛の解釈(シンポジウム:機能性胃腸症(Functional Dyspepsia)の病態を巡る脳腸相関,2008年,第49回日本心身医学会総会(札幌))
- 消化管機能からみた腹部膨満感,上腹部痛の解釈
- ショウカカン キノウ カラ ミタ フクブボウマンカン ジョウ フクブツウ ノ カイシャク
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Abstract
Gastric physiological dysfunction such as hypersensitiyity and motility disorder play an important role in pathogenesis of functional dyspepsia. However, the mechanisms inducing bloating feeling and epigastric pain remain unclear, since the relationship between pathophisiology and symptom has not been discussed enough. Our investigation using both the barostat method as a gold standard and the drinking test as an easy method, clarified an accomplishment of gastric accommodation induced postprandial bloating feeling. It was also elucidated that a gastric acid secretion inhibitor improved dyspeptic symptom by increasing the gastric perception threshold against intragastric distention, and prokinetic drugs did by increasing the threshold volume inducing bloating feeling. The drinking test is expected as a clinical useful tool for exploring gastric perception and motor function, though there are several problems including standardization of methodology to be solved. Because this method might have a potency to investigate the effects of various stressors upon gastric function, objective analyses on the relationship between psychosocial factors and dyspeptic symptoms would be expected.
Journal
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- Japanese Journal of Psychosomatic Medicine
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Japanese Journal of Psychosomatic Medicine 49 (7), 799-806, 2009
Japanese Society of Psychosomatic Medicine
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Details 詳細情報について
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- CRID
- 1390282679866899968
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- NII Article ID
- 110007331044
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- NII Book ID
- AN00121636
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- ISSN
- 21895996
- 03850307
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- NDL BIB ID
- 10256183
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed