Characteristics and Therapeutic Strategy for Japanese Type 2 Diabetic Patients Complicated by Metabolic Syndrome(Progress of the Treatment of Metabolic Syndrome)

  • Tajiri Yuji
    Division of Endocrinology and Metabolism, Kurume University School of Medicine

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  • メタボリックシンドロームを合併した日本人2型糖尿病の特徴とその予防(メタボリックシンドロームの治療の進歩,2012年,第53回日本心身医学会総会ならびに学術講演会(鹿児島))
  • メタボリックシンドロームを合併した日本人2型糖尿病の特徴とその予防
  • メタボリックシンドローム オ ガッペイ シタ ニホンジン 2ガタ トウニョウビョウ ノ トクチョウ ト ソノ ヨボウ

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Abstract

Metabolic syndrome (MetS) was first introduced in 2005, and has now been very popular in Japan together with the special health care system targeted to the coaching of diet and exercise in MetS patients. Because MetS is recognized as a high risk group for the future cardiovascular disease (CVD), the life-style modification for the prevention of CVD is the most urgent and important issue in MetS patients. On the other hand, type 2 diabetic patients have recently become obese in spite of its stereotypically lean feature in Japan. It is thus reported that almost half portion of Japanese type diabetic patients are now complicated by MetS. Therefore, treatment for diabetes should now be performed taking the influence of the background coexistence with MetS into account, including both coaching of life-style and the selection of anti-diabetic agents. In this review, we have briefly summarized the characteristics of Japanese diabetic patients complicated by MetS from the aspect of either inflammation (atherosclerosis) or body composition. Furthermore, some anti-diabetic agents have been described with regard to its unique actions for the treatment of MetS.

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