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Cardiac Sympathetic Activity Assessed by Heart Rate Variability Indicates Myocardial Ischemia on Cold Exposure in Diabetes
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- Sasaki Keita
- School of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan
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- Matsushita Shonosuke
- Graduate School of Comprehensive Human Science, Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan
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- Sato Fujio
- Graduate School of Comprehensive Human Science, Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan
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- Tokunaga Chiho
- Graduate School of Comprehensive Human Science, Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan
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- Hyodo Kazuyuki
- High Energy Accelerator Research Organization: KEK, Tsukuba, Ibaraki, Japan
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- Sakakibara Yuzuru
- Graduate School of Comprehensive Human Science, Department of Cardiovascular Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan
Bibliographic Information
- Other Title
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- 心臓交感神経指標を用いた寒冷負荷による糖尿病心筋虚血リスクの評価
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Description
Measurement of heart rate variability (HRV) is a non-invasive technique that can be used to investigate functioning of the autonomic nervous system, especially the balance between sympathetic and vagal activities. It is reported that dilatation of coronary microcirculation by augmentation of sympathetic nerve activity (SNA) caused by cold exposure was impaired in diabetes. The question of whether or not SNA in HRV could respond to coronary ischemia was evaluated by cold exposure in diabetic rats. It was found that diabetes with weight loss significantly increased SNA both in baseline and cold exposure, compared with control. A correspondence was also found with coronary ischemia. It can be concluded that measurement of HRV may provide useful information regarding the coronary risk of cold exposure in diabetes. (*English translation of J Jpn Coll Angiol 2012; 52: 295-301)
Journal
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- Annals of Vascular Diseases
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Annals of Vascular Diseases 6 (3), 583-589, 2013
The Editorial Committee of Annals of Vascular Diseases
