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Circadian rhythm of human salivary chromogranin A
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- DEN Rei
- Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine
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- TODA Masahiro
- Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine
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- NAGASAWA Shingo
- Yanaihara Institute Inc.
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- KITAMURA Kazuyuki
- Yanaihara Institute Inc.
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- MORIMOTO Kanehisa
- Department of Social and Environmental Medicine, Osaka University Graduate School of Medicine
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Description
We investigated the circadian rhythm of chromogranin A (CgA) concentrations in saliva and blood samples from 40 male college students collected at 7 : 00, 8 : 00, 10 : 30, 12 : 30, 17 : 30, and 22 : 30. CgA concentrations were determined by ELISA. Salivary CgA levels peaked upon awakening, and then quickly decreased to the nadir after 1 hour and maintained a low level throughout the day. On the other hand, plasma CgA did not show any obvious circadian rhythm. These findings suggest that salivary and plasma CgA has different routes of secretion.
Journal
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- Biomedical Research
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Biomedical Research 28 (1), 57-60, 2007
Biomedical Research Press
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Keywords
Details 詳細情報について
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- CRID
- 1390282679877983232
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- NII Article ID
- 130004903726
- 80017910671
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- COI
- 1:CAS:528:DC%2BD2sXjtFehs7o%3D
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- ISSN
- 1880313X
- 03886107
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- PubMed
- 17379958
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- Text Lang
- en
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- Article Type
- journal article
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- Data Source
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- KAKEN
- OpenAIRE
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- Abstract License Flag
- Disallowed