糖尿病性血管病変への血液凝固線溶系の関与

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タイトル別名
  • Dynamic Changes of Coagulation-fibrinolytic System in Diabetics
  • トウニョウビョウセイ ケッカン ビョウヘン エ ノ ケツエキ ギョウコ センヨ

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抄録

Coagulation-fibrinolytic activities were assayed in 45 diabetics. Platelet Factor 4 increased in 77.8 antithrombin III decreased in 61.5%, fibrinogen increased in 100% and antiplasmin decreased in 65.9% of all cases.<BR>A relative coagulative tendency without comparable in fibrinolysis seemed to exist in diabeticsirrespective of age, duration, treatment and serum lipid level.<BR>These changes seem to be 7 “the preceding state of chronic low grade disseminated intravascular coagulation”(Ultin, O. N.: 1975) and can possibly contribute to the pathogenesis of the diabetic vascular complications, especially of microangiopathy.

収録刊行物

  • 糖尿病

    糖尿病 20 (6), 728-735, 1977

    一般社団法人 日本糖尿病学会

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