Clinical Features and Treatment Strategies for Infectious Diseases in Patients with Diabetes Mellitus

DOI Web Site 15 References
  • Yoneda Masayasu
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
  • Fujikawa Rumi
    Grand Tower Medical Court
  • Oki Kenji
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
  • Nakashima Reiko
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
  • Nojima Hideki
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
  • Jitsuiki Kuniaki
    市立三次中央病院内科
  • Nakanishi Shuhei
    University of Helsinki
  • Yamane Kiminori
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University
  • Kohno Nobuoki
    Department of Molecular and Internal Medicine, Graduate School of Biomedical Sciences, Hiroshima University

Bibliographic Information

Other Title
  • 糖尿病患者における感染症の特徴およびその対策
  • トウニョウビョウ カンジャ ニ オケル カンセンショウ ノ トクチョウ オヨビ ソノ タイサク

Search this article

Description

The clinical features of 207 patients with diabetes mellitus who required hospitalization for the treatment or prevention of infections were investigated to consider effective strategies for the treatment of infections in diabetic patients. The most frequent type of infection was respiratory infection (41%), followed by urinary tract infection (24%) and skin/soft tissue infections (17%). When the subjects were divided by the leukocyte count and serum CRP level into mild, moderate and severe groups, the severe group had higher random blood glucose levels and required higher daily total insulin doses. There was also a significant association between the severity of infection and the incidence of ketosis or ketoacidosis. The most common causative microorganisms of pneumonia in the diabetic patients were methicillin-resistant Staphylococcus aureus (MRSA), Klebsiella pneumoniae, Streptococcus pneumoniae, Pseudomonas aeruginosa and Mycoplasma (in descending order). Because severe infections complicating diabetes mellitus can induce marked elevation of the blood glucose levels as well as increase the risk of complication by ketosis or ketoacidosis, diabetic patients with infections need immediate amelioration of the abnormal glucose metabolism, identification of the pathogenic microorganism and treatment with appropriate antibiotics.

Journal

References(15)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top