A Case of Glucagonoma with Skin Lesions, Anemia, and Hypoaminoacidemia Markedly Improved by Medical Therapy

DOI Web Site 16 References
  • Ohkuma Toshiaki
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Iwase Masanori
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Idewaki Yasuhiro
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University Department of Internal Medicine (Diabetes), Nippon Steel Yawata Memorial Hospital
  • Kikuchi Yohei
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Fujii Hiroki
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Oku Miwako
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Morimoto Shoko
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Doi Yasufumi
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University
  • Nakamura Udai
    Department of Internal Medicine (Diabetes), Nippon Steel Yawata Memorial Hospital
  • Iida Mitsuo
    Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University

Bibliographic Information

Other Title
  • 内科的治療により皮膚症状，貧血，低アミノ酸血症が著明に改善したグルカゴノーマの1例
  • 症例報告(九州地方会推薦) 内科的治療により皮膚症状,貧血,低アミノ酸血症が著明に改善したグルカゴノーマの1例
  • ショウレイ ホウコク キュウシュウ チホウカイ スイセン ナイカテキ チリョウ ニ ヨリ ヒフ ショウジョウ ヒンケツ テイアミノサン ケツショウ ガ チョメイ ニ カイゼン シタ グルカゴノーマ ノ 1レイ

Search this article

Abstract

We report a rare case of glucagonoma in the elderly ameliorated by medical therapy, including anabolic steroid.<br>A 74-year-old woman seen for necrolytic migratory erythema and diagnosed with glucagonoma due to hyperglucagonemia (13,000 pg/ml) and a pancreas-body tumor 3 cm in diameter also had multiple micrometastases to the liver, deep venous thrombosis, and pulmonary embolism. Her poor general condition of 16.9 kg/m2 BMI, 1.5 g/dl serum albumin, and 6.8 g/dl hemoglobin was improved by treatment with octreotide, which decreased plasma glucagon to 1,500 pg/ml and amino acid supplementation, which markedly improved necrolytic migratory erythema. To sufficiently improve hypoalbuminemia and anemia, we administered the anabolic steroid metenolone, which ameliorated hypoaminoacidemia, hypoalbuminemia, and anemia, with serum albumin rising to 2.3 g/dl and Hb to 8.5 g/dl. Insulin therapy was required to manage hyperglycemia associated with reduced endogenous insulin secretion.

Journal

References(16)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top