Change of Discomfort of the Hypochondrium(Kyo-kyo-kuman) by Administration of Kampo Formula with Bupleuri Radix(Saiko-zai), and Biochemical and Psychiatric Relevance.

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  • “柴胡剤”投与による胸脇苦満の変化と生化学的・精神医学的検討
  • リンショウ ホウコク サイコザイ トウヨ ニ ヨル キョウキョウクマン ノ ヘンカ ト セイカガクテキ セイシン イガクテキ ケントウ

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Abstract

We investigated the change of “Kyo-kyo-kuman, ” after the administration of Saiko-zai (including Bupleuri Radix) or Non-saiko-zai (not including Bupleuri Radix). Subjects were 44 patients (7 males, 37 females, with a mean age of 42.8±16.4). We evaluated their levels of the Kyo-kyo-kuman, with blood biochemical tests, their depressive levels using Zung's Self Depression Scale (SDS), and their subjective well-being levels using the Subjective Well-being Inventory (SUBI) scale, at baseline and 3 and 6 months after the administration of Kampo formula. In the S-group (20 patients), administered Saiko-zai for 6 months, the K-scale (Keio's Kyo-kyo-kuman scale) scores showed significant decreases at 3 and 6 months. In the C-group (16 patients), administered Non-saiko-zai for 6 months, the K-scale scores did not change significantly. There was a statistically significant decrease in the K-scale scores of the patients of S-group as compared to the patients of C-group. The decreases in the left K-scale scores correlated significantly with the rises in plasma protein concentrations.

Journal

  • Kampo Medicine

    Kampo Medicine 53 (1/2), 47-54, 2002

    The Japan Society for Oriental Medicine

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