Prevalence of Glucose Intolerance in Stroke Patients With Unknown Diabetes Status in Recovery Rehabilitation Ward and the Clinical Significance of Its Diagnosis

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  • Mori Toshiko
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital Department of Rehabilitation Medicine, Edogawa Hospital
  • Matsumoto Suzuko
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Omoto Takashi
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Shinozaki Masahiro
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Nishio Shinya
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Antoku Shinichi
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Abe Mariko
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Mifune Mizuo
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Shinkai Yasuhisa
    Department of Neurology, Edogawa Hospital
  • Naritaka Heiji
    Department of Neurosurgery, Edogawa Hospital
  • Togane Michiko
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital
  • Ito Hiroyuki
    Department of Diabetes, Metabolism and Kidney Disease, Edogawa Hospital

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Other Title
  • 脳卒中後の回復期リハビリテーションにおける糖尿病未診断患者の耐糖能異常の頻度と臨床的意義

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<p>We assessed the prevalence and role of abnormal glucose tolerance in subacute stroke patients with undiagnosed diabetes mellitus (DM). An oral glucose tolerance test was performed for 132 post-stroke patients in a rehabilitation ward, and 19.7 % of them were newly diagnosed with DM, while 44.7 % had impaired glucose tolerance (IGT), and 35.6 % had normal glucose tolerance (NGT). The clinical features were compared between the non-diabetic group, consisting of patients with NGT or IGT, and the diabetic group. The age, body mass index, renal function, and intima-media thickness of the carotid artery did not substantially differ between the two groups. Greater proportions of the diabetic group had hypertension and dyslipidemia than the non-diabetic group. The fasting blood glucose (FBG), 2-hour post-meal blood glucose (2hBG), C-peptide immunoreactivity, HbA1c and carotid artery plaque area were all significantly higher in the diabetic group. In cases presenting with FBG, 2hBG or HbA1c levels that are more than 101 mg/dL, 124 mg/dL, 6.1 %, respectively, a 75gOGTT would therefore be useful to detect DM cased that have previously remained undiagnosed.</p>

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