Two Cases of RS3PE Syndrome Complicated by Type 2 Diabetes with Preceding Deterioration of Glycemic Control
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- Gocho Naoki
- Diabetes Center, Ebina General Hospital
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- Okada Chiho
- Diabetes Center, Ebina General Hospital
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- Aoki Ema
- Diabetes Center, Ebina General Hospital
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- Hirashima Takeshi
- Diabetes Center, Ebina General Hospital
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- Tanaka Hideki
- Diabetes Center, Ebina General Hospital
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- Suzuki Natsuko
- Diabetes Center, Ebina General Hospital
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- Omori Yasue
- Diabetes Center, Ebina General Hospital
Bibliographic Information
- Other Title
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- 血糖コントロール悪化が先行した後にRS3PE症候群を発症した2型糖尿病の2症例
- 症例報告 血糖コントロール悪化が先行した後にRS3PE症候群を発症した2型糖尿病の2症例
- ショウレイ ホウコク ケットウ コントロール アッカ ガ センコウ シタ アト ニ RS3PE ショウコウグン オ ハッショウ シタ 2ガタ トウニョウビョウ ノ 2 ショウレイ
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Description
Remitting seronegative symmetrical synovitis with pitting edema (abbreviated RS3PE) is a syndrome characterized by symmetric polyarthritis, synovitis and acute pitting edema of the hands and feet that primarily occurs in elderly patients. Recently, the number of case reports of RS3PE syndrome associated with diabetes has increased, especially in cases involving DPP-4 inhibitors. We herein report the cases of two patients with RS3PE syndrome, one of whom was treated with a DPP-4 inhibitor and the other was not, who showed different clinical courses. Case 1 involved a 79-year-old female with type 2 diabetes who suffered from bilateral edema of the hands and feet with upper arm pain in whom deterioration of diabetes control subsequently occurred. She had been prescribed a DPP-4 inhibitor five months earlier. We made a diagnosis of RS3PE syndrome and initiated steroid therapy; however, the patient was refractory to the treatment and consecutively required high-dose steroids. Case 2 involved a 63-year-old female with type 2 diabetes who was prescribed insulin treatment without a DPP-4 inhibitor. She complained of bilateral stiff fingers, knee joint pain and edema of the hands and feet. After receiving a diagnosis of RS3PE syndrome, the patient was treated with steroid therapy. Since her symptoms disappeared quickly, the dose of steroids was gradually tapered and stopped three years after the initiation of treatment.
Journal
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- Journal of the Japan Diabetes Society
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Journal of the Japan Diabetes Society 56 (11), 874-880, 2013
THE JAPAN DIABETES SOCIETY
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Details 詳細情報について
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- CRID
- 1390282679884887936
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- NII Article ID
- 130004905374
- 40019898655
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- NII Book ID
- AN00166576
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- ISSN
- 1881588X
- 0021437X
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- NDL BIB ID
- 025062354
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- CiNii Articles
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- Abstract License Flag
- Disallowed