書誌事項
- タイトル別名
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- A Case of Severe Hypoglycemia Caused by Excessive Alcohol Intake with Subclinical Hypothalamus-Pituitary-Adrenal Axis Suppression
- ショウレイ ホウコク センザイテキ ナ カスイタイ ・ フクジン ヒシツ キノウ ヨクセイ ジョウタイ ニ ハッショウ シタ ジュウトク ナ アルコールセイ テイケットウ ノ 1レイ
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We report on a 67-year-old woman who suffered from severe hypoglycemia caused by excessive alcohol consumption. She was a heavy drinker from her young adulthood and had been treated with oral prednisolone for rheumatoid arthritis since 1990. In August 2007, she was found comatose in the morning after binge drinking and was transferred to our hospital. Since she was found to be severely hypoglycemic (plasma glucose 8 mg/dl, immunoreactive insulin 0.6 μU/ml) and she recovered consciousness with the intravenous administration of glucose, her diagnosis was hypoglycemic coma. Thereafter, she ate regular meals and quit drinking, with no recurrence of hypoglycemia. A fasting test demonstrated that hypoglycemia unawareness occurred at 40 hours after the start, and a rapid ACTH loading test demonstrated a low cortisol response. Thus, it was suggested that she might experience hypoglycemia unawareness during her daily life because of malnutrition due to chronic alcohol consumption, and subclinical hypothalamic-pituitary-adrenal axis suppression due to oral steroids. Given this background, we concluded that excess alcohol intake induced hypoglycemic coma in this patient through inhibition of gluconeogenesis.<br>
収録刊行物
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- 糖尿病
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糖尿病 55 (9), 705-709, 2012
一般社団法人 日本糖尿病学会
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詳細情報 詳細情報について
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- CRID
- 1390282679885428352
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- NII論文ID
- 130004511334
- 10031136850
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- NII書誌ID
- AN00166576
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- ISSN
- 1881588X
- 0021437X
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- NDL書誌ID
- 024019468
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可