A Case of Laryngeal Granuloma Successfully Treated with Kairosan

  • SEKIYA Nobuyasu
    Department of Frontier Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University
  • NAMIKI Takao
    Department of Frontier Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University
  • KASAHARA Yuji
    Department of Frontier Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University
  • OKAWA Toru
    Department of Otolaryngology/Head and Neck Surgery, Graduate School of Medicine, Chiba University
  • CHINO Atsushi
    Department of Frontier Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University
  • OHNO Kenji
    Department of Frontier Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University
  • HIRASAKI Yoshiro
    Department of Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University
  • TERASAWA Katsutoshi
    Department of Japanese Oriental (Kampo) Medicine, Graduate School of Medicine, Chiba University

Bibliographic Information

Other Title
  • 解労散が奏効した喉頭肉芽腫の一例
  • 臨床報告 解労散が奏効した喉頭肉芽腫の一例
  • リンショウ ホウコク カイロウサン ガ ソウコウシタ コウトウ ニクゲシュ ノ イチレイ

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Description

Laryngeal granulomas which grow in the rear of the vocal cords can be a refractory and recurrent condition, because of various pathogeneses and a lack of established treatment guidelines. We experienced a laryngeal granuloma case which recurred repeatedly, and was resistant to modern medicinal treatment. The laryngeal granuloma recurred after microlaryngosurgery. And though a second microlaryngosurgery and laser cauterization was done, followed by prescription of lansoprazole, tranilast, chlarithromycin and inhalation of fluticasone propionate, the laryngeal granuloma recurred once more. Thus, we tried Kampo medicines at the this time. Hangekobokuto, saishakurikkunshito and keikyososooushimbuto were stopped due to lack of efficacy on the ganuloma, and the Kampo formulation was changed to kairosan. Three weeks after changing formulation, the granuloma was no longer seen with laryngeal fiberscopy. And to-date, recurrence of the granuloma has not been confirmed. This case suggests that fatigue, body weight loss, bilateral Kyokyo-kuman (discomfort of the hypochondrium), bilateral excessive strain of abdominal muscles, pulsation of both the upper and lower navel, and tympanitic sound in upper abdomen may be clinical indications for kairosan.

Journal

  • Kampo Medicine

    Kampo Medicine 59 (2), 297-301, 2008

    The Japan Society for Oriental Medicine

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