Effects of Toki-shakuyaku-san on Immune Complexes Binding to Macrophages in vitro. Studies on the Combination of Angelica and Atractylodes (lancea) of Different Origin.

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Other Title
  • 免疫複合体除去能に対する当帰しゃく薬散の作用　数種の当帰，じゅつによる比較検討
  • メンエキ フクゴウタイ ジョキョノウ ニ タイスル トウキシャクヤクサン ノ
  • Studies on the Combination of <i>Angelica</i> and <i>Atractylodes</i> (<i>lancea</i>) of Different Origin
  • 数種の当帰, 朮による比較検討

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Abstract

For the purpose of establishing a method for evaluation of crude drugs, we demon strated the effect of aqueous extracts from the roots of seven different (types of) Angelicae (“Toki”) and rhizomes of seven different (types of) Atractylodes (lancea) (“Jutsu”) on the binding of immune complexes to macrophages. Among the extracts from “Toki”, extract of Angelica acutiloba Kitagawa (harvested in Nara Prefecture and the Hokuriku district in Japan) had the most potent enhancing activity on the binding. Among the extracts from “Juste”, extract of Atractylodes lancea DC, (An Hui Sheng in China) had the most potent enhancing activity. However, when the extracts were made from the codecoction of Angelica and Atractylodes lancea, the enhancing activities were varied. These results suggest that the combination of crude drugs tays an important role in the appearance of the pharmacological activities.

Journal

  • Kampo Medicine

    Kampo Medicine 44 (4), 509-516, 1994

    The Japan Society for Oriental Medicine

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