A Case of Hypothalamic Syndrome Complicated by Rhabdomyolysis and Pulmonary Embolism on Subsequent Hyperglycemic Hyperosmolar Syndrome
-
- Gocho Naoki
- Diabetes Center, Ebina General Hospital
-
- Sato Yoshitaka
- Diabetes Center, Ebina General Hospital
-
- Kondo Tomoko
- Diabetes Center, Ebina General Hospital
-
- Hirashima Takeshi
- Diabetes Center, Ebina General Hospital
-
- Tagawa Akihiro
- Diabetes Center, Ebina General Hospital
-
- Tanaka Hideki
- Diabetes Center, Ebina General Hospital
-
- Suzuki Natsuko
- Diabetes Center, Ebina General Hospital
-
- Omori Yasue
- Diabetes Center, Ebina General Hospital
Bibliographic Information
- Other Title
-
- 高血糖高浸透圧症候群に横紋筋融解症,肺塞栓症を合併した視床下部症候群の1例
- 症例報告 高血糖高浸透圧症候群に横紋筋融解症,肺塞栓症を合併した視床下部症候群の1例
- ショウレイ ホウコク コウケットウ コウシントウアツ ショウコウグン ニ オウモンキン ユウカイショウ,ハイ ソクセンショウ オ ガッペイ シタ シショウカブ ショウコウグン ノ 1レイ
Search this article
Abstract
A 47-year-old man who had undergone hypothalamic meningioma surgery one year earlier and postoperative hormone replacement therapy for panhypopituitarism and diabetes insipidus was seen for general fatigue and lethargy. Laboratory examination showed markedly elevated plasma glucose with few ketone bodies. Chest computed tomography (CT) showed ground-glass opacity of the lung. He was admitted in an emergency and diagnosed with hyperglycemic hyperosmolar state and pneumonia, for which he was administered continuous intravenous insulin infusion and antibiotics. Although his general condition improved immediately as plasma glucose decreased, laboratory examination showed severely elevated creatine phosphokinase and serum and urine myoglobin, indicating rhabdomyolysis. Early volume loading was started and rhabdomyolysis was cured without severe acute kidney injury. On day 7, he suffered sudden chest pain with hypoxemia. Emergency CT with contrast medium showed multiple bilateral perfusion defects consistent with pulmonary emboli and underlying deep vein thrombosis of the lower left leg. Anticoagulation therapy with heparin and warfarin was conducted immediately. His respiratory status improved gradually as pulmonary emoboli decreased. This report is a rare case of hypothalamic syndrome complicated by rhabdomyolysis and pulmonary embolism on subsequent hyperglycemic hyperosmolar syndrome.<br>
Journal
-
- Journal of the Japan Diabetes Society
-
Journal of the Japan Diabetes Society 55 (8), 614-620, 2012
THE JAPAN DIABETES SOCIETY
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282679885686144
-
- NII Article ID
- 10031123016
-
- NII Book ID
- AN00166576
-
- ISSN
- 1881588X
- 0021437X
-
- NDL BIB ID
- 023965354
-
- Text Lang
- ja
-
- Data Source
-
- JaLC
- NDL
- CiNii Articles
-
- Abstract License Flag
- Disallowed